Publications

Ahmad T, Vullhorst D, Chaudhuri R, Guardia MC, Chaudhary N, Karavanova I, Bonifacino JS, Buonanno B. Transcytosis and trans-synaptic retention by postsynaptic ErbB4 underlie axonal accumulation of NRG3. (JBC minor revision).

Islam K, A-Elgadir TME, Afaq S, Ahmad T*, Iqbal J*. Molecular and clinical aspects of COVID-19 vaccines and other therapeutic interventions apropos emerging variants of concern. Frontiers in pharmacology. 2021 Dec 23;12:778219. doi: 10.3389/fphar.2021.778219. eCollection 2021.

Arora S, Singh P, Ahmad S, Ahmad T, Dohare R, Saleh A, Alrumaihi AF, Rahmani HA, Syed AM. Comprehensive integrative analysis reveals the association of KLF4 with macrophage infiltration and polarization in lung cancer microenvironment. Cells. 2021 Aug 14;10(8):2091. doi: 10.3390/cells10082091.

Sharma A, Ahmad S, Ahmad T, Ali S, Syed AM. Mitochondrial Dynamics and Mitophagy in lung disorders. Life Sci. 2021 Nov 1;284:119876. doi: 10.1016/j.lfs.2021.119876. Epub 2021 Aug 10.

Agrawal, A., Ahmad, T. Editorial on the Research Topic. Mitochondrial Calcium in Cell Death and Disease. Mitochondrion. 2021 Jul;59:154-156. doi:
10.1016/j.mito.2021.04.008.

Bansal, N., Chitkara, M., Azmi, I., Iqbal, J., & Ahmad, T*. CASSPIT: A simple CRISPR Diagnosis of SARS-CoV-2 detection in saliva samples. Commentary. Journal of Clinical Trials (in press). 2021. *co-corresponding author.

Azmi I, Faizan MI, Kumar R, Raj Yadav S, Chaudhary N, Kumar Singh D, Butola R, Ganotra A, Datt Joshi G, Deep Jhingan G, Iqbal J, Joshi MC, Ahmad T. A Saliva-Based RNA Extraction-Free Workflow Integrated With Cas13a for SARS-CoV-2 Detection. Front Cell Infect Microbiol. 2021 Mar 16;11:632646. doi: 10.3389/fcimb.2021.632646. PMID: 33796478; PMCID: PMC8009180. *co-corresponding author.

Rana M, Arif R, Khan FI, Maurya V, Singh R, Faizan I, Yasmeen S, Dar SH, Alam R, Sahu A, Ahmad, T, Rahisuddin. Pyrazoline analogs as potential anticancer agents and their apoptosis, molecular docking, MD simulation, DNA binding and antioxidant studies. Bioorganic Chemistry. 2021,104665. https://doi.org/10.1016/j.bioorg.2021.104665.

Faizan I, Ahmad T. Altered mitochondrial calcium handling and cell death by necroptosis: An emerging paradigm. Mitochondrion. 2020 Dec 16:S1567-7249(20)30227-0. doi: 10.1016/j.mito.2020.12.004. Epub ahead of print. PMID: 33340710. *corresponding author.

Ahmad T*, Chaudhuri R, Joshi MC, Almatroudi A, Rahmani AH, and Ali SM. COVID-19: The Emerging Immunopathological Determinants for Recovery or Death. Frontiers in microbiology. 2020 Dec 1;11:588409. doi: 10.3389/fmicb.2020.588409. eCollection 2020. *corresponding author.

Rai A, Ahmad T, Parveen S, Parveen S, Faizan MI, Ali S. Expression of transforming growth factor beta in oral submucous fibrosis. J Oral Biol Craniofac Res. 2020;10(2):166- 170. doi: 10.1016/j.jobcr.2020.03.015.

Kulshreshtha A, Singh S, Ahmad M, Khanna K, Ahmad T, Agrawal A, Ghosh B. Simvastatin mediates inhibition of exosome synthesis, localization and secretion via multicomponent interventions. Sci Rep. 2019, 1637-1642. DOI: 10.1101/366211.

Vullhorst D, Ahmad T, Karavanova A, Keating C, and Buonanno A. Structural Similarities Between Neuregulin 1-3 Isoforms Determine their Subcellular Distribution and Signaling Mode in Central Neurons. J Neurosci. 2017 May 24;37(21):5232-5249.

Ahmad T, Sundar IK, Tormos AM, Lerner CA, Gerloff J, Yao H, Rahman I. Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2017 Jan;56(1):38-49.

Pattnaik B, Bodas M, Bhatraju N, Ahmad T, Pant R, Guleria R, Ghosh B & Agrawal A. IL-4 promotes ADMA accumulation, oxo-nitrative stress and hypoxic response-induced mitochondrial loss in airway epithelial cells. J Allergy Clin Immunol. 2016 Jul;138(1):130- 141.e9.

Ariazi J, Benowitz A, De Biasi V, Den Boer ML, Cherqui S, Cui H, Douillet N, Eugenin EA, Favre D, Goodman S, Gousset K, Hanein D, Israel DI, Kimura S, Kirkpatrick RB, Kuhn N, Jeong C, Lou E, Mailliard R, Maio S, Okafo G, Osswald M, Pasquier J, Polak R, Pradel G, de Rooij B, Schaeffer P, Skeberdis VA, Smith IF, Tanveer A, Volkmann N, Wu Z, Zurzolo C. Tunneling Nanotubes and Gap Junctions – their role in long-range intercellular communication during development, health, and disease conditions. Frontiers of Neuroscience. 2017. 2017; 10: 333.

Lerner CA, Rutagarama P, Ahmad T, Sundar IK, Elder A, Rahman I. Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts. Biochemical and biophysical research communications. 2016 477(4):620-625.

Ahmad T, Sundar IK, Lerner CA, Gerloff J, Tormos AM, Yao H, Rahman I. Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence. FASEB J. 2015 Mar 19. pii: fj.14-268276.

Sundar IK, Ahmad T, Yao H, Hwang JW, Gerloff J, Lawrence BP, Sellix MT, Rahman I. Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD. Sci Rep. 2015 Apr 29; 4:9927.

Singh VP, Aggarwal R, Singh S, Banik A, Ahmad T, Patnaik BR, Nappanveettil G, Singh KP, Aggarwal ML, Ghosh B, Agrawal A. Metabolic Syndrome is Associated with Increased Oxo-nitrative Stress and Asthma-like Changes in Lungs. PLoS One. 2015 Jun 22;10(6): e0129850.

Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari BK, Jha KA, Barhanpurkar AP, Wani MR, Roy SS, Mabalirajan U, Ghosh B, Agrawal A. Miro1 Regulates Intercellular Mitochondrial Transport and Enhances Mesenchymal Stem Cell Rescue Efficiency. EMBO J. 2014 May 2; 33(9): 994-1010.

Yao H, Sundar IK, Ahmad T, Lerner C, Gerloff J, Friedman AE, Phipps RP, Sime PJ, McBurney MW, Guarente L, Rahman I. SIRT1 protects against cigarette smoke-induced lung oxidative stress via FOXO3-dependent mechanism. Am J Physiol Lung Cell Mol Physiol. 2014 May 1; 306 (9): L816-28.

Mabalirajan U, Ahmad T, Rehman R, Agrawal A and Ghosh B. Baicalein reduces airway injury in allergen and IL-13 induced airway inflammation. PLoS One 2013 Apr 30; 8(4):e62916.

Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem GD, Singh S, Dinda AK, Biswal S, Agrawal A, Ghosh B. 12/15-lipoxygenase expressed in non-epithelial cells causes’ airway epithelial injury in asthma. Scientific reports, 2013; 3:1540.

Mabalirajan U, Rehman R, Ahmad T, Kumar S, Singh S, Leishangthem GD, Aich J, Kumar M, Khanna K, Singh VP, Dinda AK, Biswal S, Agrawal A, Ghosh B. Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Scientific reports 2013; 3:1349.

Ahmad T, Aggarwal K, Pattnaik B, Mukherjee S, Sethi T, Tiwari BK, Kumar M, Micheal A, Mabalirajan U, Ghosh B, Sinha Roy S, Agrawal A. Computational Classification of Mitochondrial Shapes Reflects Stress and Redox State. CDDis, 2013 Jan 17; 4:e461. doi: 10.1038/cddis.2012.213.

Kulshreshtha A, Ahmad T, Agrawal A, Ghosh B. Proinflammatory role of epithelial cell derived exosomes in allergic airway inflammation. JACI, 2013 Feb 13. pii: S0091- 6749(12)03565-8.

Ahmad T, Kumar M, Mabalirajan U, Pattnaik B, Aggarwal S, Singh R, Singh S, Mukerji M, Ghosh B, Agrawal A. Hypoxia response in asthma: differential modulation on inflammation and epithelial injury. Am. J. Respir. Cell Mol. Biol. 2012; 47, 1-10.

Sharma A, Kumar M, Ahmad T, Mabalirajan U, Aich J, Agrawal A, Ghosh B. Antagonism of mmu-mir-106a attenuates asthma features in allergic murine model. J. Appl. Physiol. 2012; 113, 459-464.

Aich J, Mabalirajan U, Ahmad T, Agrawal A, Ghosh B. Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway
inflammation. Nat. Commun. 2012; 3:877.

Aich J, Mabalirajan U, Ahmad T, Khanna K, Rehman R, Agrawal A, Ghosh B. Resveratrol attenuates experimental allergic asthma in mice by restoring inositol polyphosphate 4 phosphatase (INPP4A). Int. Immunopharmacol. 2012; 14, 438-443.

Agrawal A, Mabalirajan U, Ahmad T, and Ghosh, B. Emerging interface between metabolic syndrome and asthma. Am. J. Respir. Cell Mol. Biol. 2011. 44, 270-275.

Ahmad T, Mabalirajan U, Hasija K, Ghosh B, Agrawal A. Mepacrine treatment attenuates allergic airway remodeling segregated from airway inflammation in mice. Int. Immunopharmacol. 2011; 11, 74-78.

Ahmad T, Mabalirajan U, Sharma A, Aich J, Makhija L, Ghosh B, Agrawal A. Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. Am. J. Respir. Cell Mol. Biol. 2011; 44, 531-539.

Kumar M, Ahmad T, Sharma A, Mabalirajan U, Kulshreshtha A, Agrawal A, Ghosh B. Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation. J. Allergy Clin. Immunol. 2011; 128, 1077-1085.

Ahmad T, Mabalirajan U, Ghosh B, Agrawal A. Altered asymmetric dimethyl arginine metabolism in allergically inflamed mouse lungs. Am. J. Respir. Cell Mol. Biol. 2010; 42, 3-8.

Mabalirajan U, Ahmad T, Leishangthem GD, Dinda AK, Agrawal A, Ghosh B. L-arginine reduces mitochondrial dysfunction and airway injury in murine allergic airway inflammation. Int. Immunopharmacol. 2010; 10, 1514-1519.

Mabalirajan U, Ahmad T, Leishangthem GD, Joseph DA, Dinda AK, Agrawal A, Ghosh B. Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma. J. Allergy Clin. Immunol. 2010; 125, 626-635.

Ahmad T, Mabalirajan U, Joseph DA, Makhija L, Singh VP, Ghosh B, Agrawal A. Exhaled nitric oxide estimation by a simple and efficient noninvasive technique and its utility as a marker of airway inflammation in mice. J. Appl. Physiol. 2009; 107, 295-301.

Agrawal A, Sinha A, Ahmad T, Aich J, Singh P, Sharma A, Ghosh B. Maladaptation of critical cellular functions in asthma: bioinformatic analysis. Physiol Genomics. 2009; 40, 1-7.